•  
  vs
  Colorado Rapids Rapids
  2-0
  Lumen Field
•  
  @
  Real Salt Lake Real Salt Lake
  2-1
  America First Field
•  
  @
  St. Louis CITY SC St. Louis CITY SC
  1-0
  Energizer Park
•  
  @
  San Jose Earthquakes Earthquakes
  1-0
  PayPal Park
•  
  @
  Minnesota United Minnesota United
  0-0
  Allianz Field
•  
  @
  Houston Dynamo Dynamo
  1-0
  Shell Energy Stadium
•  
  vs
  St. Louis CITY SC St. Louis CITY SC
  4-1
  Lumen Field
•  
  vs
  FC Dallas FC Dallas
  2-1
  Lumen Field
•  
  @
  Sporting Kansas City Sporting Kansas City
  1-1
  Sporting Park
•  
  vs
  San Diego FC San Diego FC
  1-1
  Lumen Field
•  
  vs
  San Jose Earthquakes Earthquakes
  3-2
  Lumen Field
•  
  vs
  Los Angeles Galaxy Galaxy
  2-0
  Lumen Field
•  
  @
  Los Angeles FC Los Angeles FC
  1-0
  BMO Stadium
•  
  @
  Toluca Toluca
   
  Estadio Nemesio Díez Riega
•  
  vs
  Queretaro Queretaro
   
  Seattle Field
•  
  vs
  Guadalajara Guadalajara
   
  Lumen Field

Knockout (Two Legs)

•  
  @
  Vancouver Whitecaps Whitecaps
  3-0
  BC Place
•  
  vs
  Vancouver Whitecaps Whitecaps
  2-1
  ONE Spokane Stadium
•  
  @
  Tigres Tigres
  2-0
  Estadio Universitario
•  
  vs
  Tigres Tigres
  3-1
  Lumen Field

Regular Season

•  
  vs
  Portland Timbers Timbers
   
  Seattle Field
•  
  @
  Austin FC Austin FC
   
  Q2 Stadium
•  
  @
  Philadelphia Union Union
   
  Subaru Park
•  
  @
  Portland Timbers Timbers
   
  Providence Park
•  
  vs
  Vancouver Whitecaps Whitecaps
   
  Seattle Field
•  
  vs
  Austin FC Austin FC
   
  Lumen Field
•  
  @
  FC Cincinnati FC Cincinnati
   
  TQL Stadium
•  
  vs
  Chicago Fire Fire
   
  Seattle Field
•  
  vs
  New York Red Bulls Red Bulls
   
  Seattle Field
•  
  @
  Los Angeles Galaxy Galaxy
   
  Dignity Health Sports Park
•  
  @
  Colorado Rapids Rapids
   
  Dick's Sporting Goods Park
•  
  vs
  Real Salt Lake Real Salt Lake (+1)
   
  Lumen Field
•  
  vs
  Minnesota United Minnesota United
   
  Seattle Field
•  
  vs
  Sporting Kansas City Sporting Kansas City
   
  Seattle Field
•  
  @
  New England Revolution Revolution
   
  Boston Stadium
•  
  @
  FC Dallas FC Dallas
   
  Toyota Stadium
•  
  vs
  CF Montreal CF Montreal
   
  Seattle Field
•  
  @
  San Diego FC San Diego FC
   
  Snapdragon Stadium
•  
  vs
  Houston Dynamo Dynamo
   
  Seattle Field
•  
  @
  Vancouver Whitecaps Whitecaps
   
  BC Place Vancouver
•  
  vs
  Los Angeles FC Los Angeles FC
   
  Seattle Field