•  
  vs
  Real Salt Lake Real Salt Lake
  1-0
  BC Place
•  
  vs
  Cartagines Cartagines
  2-0
  BC Place
•  
  vs
  Toronto FC Toronto FC
  3-0
  BC Place
•  
  @
  Portland Timbers Timbers
  4-1
  Providence Park
•  
  vs
  Minnesota United Minnesota United
  6-0
  BC Place
•  
  vs
  San Jose Earthquakes Earthquakes
  1-0
  BC Place
•  
  vs
  Portland Timbers Timbers
  3-2
  BC Place
•  
  vs
  New York City FC New York City FC
  2-0
  BC Place
•  
  vs
  Sporting Kansas City Sporting Kansas City (+2.5)
   
  BC Place
•  
  vs
  Colorado Rapids Rapids (+1.5)
   
  BC Place
•  
  @
  Los Angeles Galaxy Galaxy
   
  Dignity Health Sports Park
•  
  @
  San Jose Earthquakes Earthquakes
   
  PayPal Park
•  
  @
  FC Dallas FC Dallas
   
  Toyota Stadium
•  
  vs
  Mazatlán Mazatlán
   
  BC Place
•  
  vs
  Juarez Juarez
   
  BC Place
•  
  @
  Tigres Tigres
   
  Estadio Universitario

Knockout (Two Legs)

•  
  vs
  Seattle Sounders Sounders
  3-0
  BC Place
•  
  @
  Seattle Sounders Sounders
  2-1
  ONE Spokane Stadium

Regular Season

•  
  @
  Houston Dynamo Dynamo
   
  Shell Energy Stadium
•  
  @
  San Diego FC San Diego FC
   
  Snapdragon Stadium
•  
  @
  Chicago Fire Fire
   
  Soldier Field
•  
  @
  FC Cincinnati FC Cincinnati
   
  TQL Stadium
•  
  @
  Minnesota United Minnesota United
   
  Allianz Field
•  
  vs
  Los Angeles FC Los Angeles FC
   
  BC Place
•  
  @
  Seattle Sounders Sounders
   
  Lumen Field
•  
  vs
  Houston Dynamo Dynamo
   
  BC Place
•  
  vs
  FC Dallas FC Dallas
   
  BC Place
•  
  @
  Sporting Kansas City Sporting Kansas City
   
  Children's Mercy Park
•  
  vs
  St. Louis CITY SC St. Louis CITY SC
   
  BC Place
•  
  vs
  Los Angeles Galaxy Galaxy
   
  BC Place
•  
  vs
  Austin FC Austin FC
   
  BC Place
•  
  @
  Real Salt Lake Real Salt Lake
   
  America First Field
•  
  vs
  D.C. United D.C. United
   
  BC Place
•  
  @
  Los Angeles FC Los Angeles FC
   
  BMO Stadium
•  
  @
  St. Louis CITY SC St. Louis CITY SC
   
  Energizer Park
•  
  @
  Austin FC Austin FC
   
  Q2 Stadium
•  
  @
  Colorado Rapids Rapids
   
  Dick's Sporting Goods Park
•  
  vs
  San Diego FC San Diego FC
   
  BC Place
•  
  vs
  Seattle Sounders Sounders
   
  BC Place
•  
  @
  CF Montreal CF Montreal
   
  Stade Saputo