Regular Season

•  
  vs
  Wolverhampton Wolverhampton
  1-0
  Old Trafford
•  
  @
  Tottenham Hotspur Tottenham Hotspur
  2-0
  Tottenham Hotspur Stadium
•  
  vs
  Nottingham Forest Nottingham Forest
  3-2
  Old Trafford
•  
  @
  Arsenal Arsenal
  3-1
  Emirates Stadium
•  
  vs
  Brighton Brighton
  3-1
  Old Trafford
•  
  @
  Burnley Burnley
  1-0
  Turf Moor
•  
  vs
  Crystal Palace Crystal Palace
  1-0
  Old Trafford
•  
  vs
  Brentford Brentford
  2-1
  Old Trafford
•  
  @
  Sheffield United Sheffield United
  2-1
  Bramall Lane
•  
  vs
  Manchester City Manchester City
  3-0
  Old Trafford
•  
  @
  Fulham Fulham
  1-0
  Craven Cottage
•  
  vs
  Luton Luton
  1-0
  Old Trafford
•  
  @
  Everton Everton
  3-0
  Goodison Park
•  
  @
  Newcastle United Newcastle United
  1-0
  St. James' Park
•  
  vs
  Chelsea Chelsea
  2-1
  Old Trafford
•  
  vs
  Bournemouth Bournemouth
  3-0
  Old Trafford
•  
  @
  Liverpool Liverpool
  0-0
  Anfield
•  
  @
  West Ham United West Ham United
  2-0
  London Stadium
•  
  vs
  Aston Villa Aston Villa
  3-2
  Old Trafford
•  
  @
  Nottingham Forest Nottingham Forest
  2-1
  City Ground
•  
  vs
  Tottenham Hotspur Tottenham Hotspur
  2-2
  Old Trafford
•  
  @
  Wolverhampton Wolverhampton
  4-3
  Molineux Stadium
•  
  vs
  West Ham United West Ham United
  3-0
  Old Trafford
•  
  @
  Aston Villa Aston Villa
  2-1
  Villa Park
•  
  @
  Luton Luton
  2-1
  Kenilworth Road
•  
  vs
  Fulham Fulham
  2-1
  Old Trafford
•  
  @
  Manchester City Manchester City
  3-1
  Etihad Stadium
•  
  vs
  Everton Everton
  2-0
  Old Trafford
•  
  @
  Brentford Brentford
  1-1
  Brentford Community Stadium
•  
  @
  Chelsea Chelsea
  4-3
  Stamford Bridge
•  
  vs
  Liverpool Liverpool
  2-2
  Old Trafford
•  
  @
  Bournemouth Bournemouth
  2-2
  Dean Court
•  
  vs
  Sheffield United Sheffield United
  4-2
  Old Trafford
•  
  vs
  Burnley Burnley
  1-1
  Old Trafford
•  
  @
  Crystal Palace Crystal Palace
  4-0
  Selhurst Park
•  
  vs
  Arsenal Arsenal (-1.5)
   
  Old Trafford
•  
  vs
  Newcastle United Newcastle United (-0.5)
   
  Old Trafford
•  
  @
  Brighton Brighton (-0.5)
   
  American Express Stadium

Pool Play

•  
  @
  Bayern München Bayern München
  4-3
  Allianz Arena
•  
  vs
  Galatasaray Galatasaray
  3-2
  Old Trafford
•  
  vs
  Copenhagen Copenhagen
  1-0
  Old Trafford
•  
  @
  Copenhagen Copenhagen
  4-3
  Parken Stadium
•  
  @
  Galatasaray Galatasaray
  3-3
  Rams Park
•  
  vs
  Bayern München Bayern München
  1-0
  Old Trafford

•  
  vs
  Crystal Palace Crystal Palace
  3-0
  Old Trafford
•  
  vs
  Newcastle United Newcastle United
  3-0
  Old Trafford
•  
  @
  Wigan Wigan
  2-0
  DW Stadium
•  
  @
  Newport County Newport County
  4-2
  Rodney Parade
•  
  @
  Nottingham Forest Nottingham Forest
  1-0
  The City Ground

Knockout

•  
  vs
  Liverpool Liverpool
  4-3
  Old Trafford
•  
  @
  Coventry Coventry
  3-3
  Wembley Stadium
•  
  @
  Manchester City Manchester City (-1.5)
   
  Wembley Stadium