•  
  vs
  Toronto FC Toronto FC
  0-0
  TQL Stadium
•  
  @
  Chicago Fire Fire
  2-1
  Soldier Field
•  
  vs
  D.C. United D.C. United
  0-0
  TQL Stadium
•  
  @
  New England Revolution Revolution
  2-1
  Gillette Stadium
•  
  vs
  New York City FC New York City FC
  1-0
  TQL Stadium
•  
  @
  Charlotte FC Charlotte FC
  1-1
  Bank of America Stadium
•  
  vs
  New York Red Bulls Red Bulls
  2-1
  TQL Stadium
•  
  @
  CF Montreal CF Montreal
  2-1
  Saputo Stadium
•  
  @
  Atlanta United FC Atlanta United FC (-0.5)
   
  Mercedes-Benz Stadium
•  
  vs
  Colorado Rapids Rapids
   
  TQL Stadium
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  @
  Columbus Crew Crew
   
  Lower.com Field
•  
  vs
  Atlanta United FC Atlanta United FC
   
  TQL Stadium
•  
  vs
  St. Louis CITY SC St. Louis CITY SC
   
  TQL Stadium
•  
  @
  Toronto FC Toronto FC
   
  BMO Field
•  
  vs
  Nashville SC Nashville SC
   
  TQL Stadium
•  
  @
  San Jose Earthquakes Earthquakes
   
  PayPal Park
•  
  vs
  Philadelphia Union Union
   
  TQL Stadium
•  
  vs
  New England Revolution Revolution
   
  TQL Stadium
•  
  @
  FC Dallas FC Dallas
   
  Toyota Stadium
•  
  @
  D.C. United D.C. United
   
  Audi Field
•  
  vs
  Inter Miami CF Inter Miami CF
   
  TQL Stadium
•  
  vs
  Charlotte FC Charlotte FC
   
  TQL Stadium
•  
  vs
  Chicago Fire Fire
   
  TQL Stadium
•  
  @
  New York Red Bulls Red Bulls
   
  Red Bull Arena
•  
  @
  Inter Miami CF Inter Miami CF
   
  Chase Stadium
•  
  vs
  CF Montreal CF Montreal
   
  TQL Stadium
•  
  vs
  Columbus Crew Crew
   
  TQL Stadium
•  
  @
  Minnesota United Minnesota United
   
  Allianz Field
•  
  @
  Nashville SC Nashville SC
   
  Geodis Park
•  
  vs
  Los Angeles FC Los Angeles FC
   
  TQL Stadium
•  
  @
  New York City FC New York City FC
   
  Yankee Stadium
•  
  vs
  Orlando City SC Orlando City SC
   
  TQL Stadium
•  
  @
  Philadelphia Union Union
   
  Subaru Park

Pool Play

•  
  vs
  Queretaro Queretaro
   
  TQL Stadium
•  
  vs
  New York City FC New York City FC
   
  TQL Stadium