•  
  vs
  Atlanta United FC Atlanta United FC
  2-0
  TQL Stadium
•  
  vs
  Universidad O&M Universidad O&M
  9-0
  TQL Stadium
•  
  @
  Minnesota United Minnesota United
  1-0
  Allianz Field
•  
  vs
  Toronto FC Toronto FC
  1-0
  TQL Stadium
•  
  @
  New England Revolution Revolution
  6-1
  Gillette Stadium
•  
  vs
  CF Montreal CF Montreal
  4-3
  TQL Stadium
•  
  @
  New York Red Bulls Red Bulls
  4-2
  Sport Illustrated Stadium
•  
  @
  Toronto FC Toronto FC
  1-1
  BMO Field
•  
  vs
  Chicago Fire Fire
  3-3
  TQL Stadium
•  
  @
  New York City FC New York City FC
  4-4
  Yankee Stadium
•  
  vs
  New York Red Bulls Red Bulls
  2-0
  TQL Stadium
•  
  @
  Chicago Fire Fire
  3-2
  Soldier Field
•  
  @
  Charlotte FC Charlotte FC (PK)
   
  Bank of America Stadium
•  
  vs
  Inter Miami CF Inter Miami CF (-0.5)
   
  TQL Stadium
•  
  @
  San Diego FC San Diego FC (-1)
   
  Snapdragon Stadium
•  
  vs
  Orlando City SC Orlando City SC
   
  TQL Stadium
•  
  vs
  Pachuca Pachuca
   
  TQL Stadium
•  
  vs
  UNAM Pumas UNAM Pumas
   
  TQL Stadium
•  
  vs
  Atlas Atlas
   
  TQL Stadium

Knockout (Two Legs)

•  
  vs
  Tigres Tigres
  3-0
  TQL Stadium
•  
  @
  Tigres Tigres
  5-1
  Estadio Universitario

Regular Season

•  
  vs
  Vancouver Whitecaps Whitecaps
   
  TQL Stadium
•  
  @
  Columbus Crew Crew
   
  ScottsMiracle-Gro Field
•  
  vs
  San Jose Earthquakes Earthquakes
   
  TQL Stadium
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  vs
  New York City FC New York City FC
   
  TQL Stadium
•  
  vs
  Seattle Sounders Sounders
   
  TQL Stadium
•  
  @
  Nashville SC Nashville SC
   
  GEODIS Park
•  
  vs
  D.C. United D.C. United
   
  TQL Stadium
•  
  @
  Philadelphia Union Union
   
  Subaru Park
•  
  vs
  Charlotte FC Charlotte FC
   
  TQL Stadium
•  
  @
  Houston Dynamo Dynamo
   
  Shell Energy Stadium
•  
  @
  CF Montreal CF Montreal
   
  Stade Saputo
•  
  @
  Atlanta United FC Atlanta United FC
   
  Mercedes-Benz Stadium
•  
  vs
  New England Revolution Revolution
   
  TQL Stadium
•  
  vs
  Columbus Crew Crew
   
  TQL Stadium
•  
  @
  D.C. United D.C. United
   
  Audi Field
•  
  @
  Inter Miami CF Inter Miami CF
   
  Nu Stadium
•  
  vs
  Philadelphia Union Union
   
  TQL Stadium
•  
  vs
  Nashville SC Nashville SC
   
  TQL Stadium