•  
  @
  Los Angeles FC Los Angeles FC
  3-0
  Los Angeles Memorial Coliseum
•  
  @
  Orlando City SC Orlando City SC
  4-2
  Inter&Co Stadium
•  
  @
  D.C. United D.C. United
  2-1
  M&T Bank Stadium
•  
  @
  Charlotte FC Charlotte FC
  0-0
  Bank of America Stadium
•  
  @
  New York City FC New York City FC
  3-2
  Yankee Stadium
•  
  vs
  Austin FC Austin FC
  2-2
  Nu Stadium
•  
  vs
  New York Red Bulls Red Bulls
  2-2
  Nu Stadium
•  
  @
  Colorado Rapids Rapids
  3-2
  Empower Field at Mile High
•  
  @
  Real Salt Lake Real Salt Lake
  2-0
  America First Field
•  
  vs
  New England Revolution Revolution
  1-1
  Nu Stadium
•  
  vs
  Orlando City SC Orlando City SC
  4-3
  Nu Stadium
•  
  @
  Toronto FC Toronto FC
  0-1   Half
  BMO Field
•  
  @
  FC Cincinnati FC Cincinnati (+0.5)
   
  TQL Stadium
•  
  vs
  Portland Timbers Timbers (+1.5)
   
  Nu Stadium
•  
  vs
  Philadelphia Union Union
   
  Nu Stadium
•  
  vs
  San Luis San Luis
   
  Nu Stadium
•  
  vs
  Monterrey Monterrey
   
  Nu Stadium
•  
  vs
  Leon Leon
   
  Nu Stadium

Knockout (Two Legs)

•  
  @
  Nashville SC Nashville SC
  0-0
  GEODIS Park
•  
  vs
  Nashville SC Nashville SC
  1-1
  Chase Stadium

Regular Season

•  
  vs
  Chicago Fire Fire
   
  Nu Stadium
•  
  @
  CF Montreal CF Montreal
   
  Stade Saputo
•  
  vs
  Columbus Crew Crew
   
  Nu Stadium
•  
  @
  Nashville SC Nashville SC
   
  GEODIS Park
•  
  @
  Philadelphia Union Union
   
  Subaru Park
•  
  vs
  Toronto FC Toronto FC
   
  Nu Stadium
•  
  vs
  CF Montreal CF Montreal
   
  Nu Stadium
•  
  vs
  Atlanta United FC Atlanta United FC
   
  Nu Stadium
•  
  @
  Chicago Fire Fire
   
  Soldier Field
•  
  vs
  Nashville SC Nashville SC
   
  Nu Stadium
•  
  vs
  San Diego FC San Diego FC
   
  Nu Stadium
•  
  @
  Columbus Crew Crew
   
  ScottsMiracle-Gro Field
•  
  vs
  D.C. United D.C. United
   
  Nu Stadium
•  
  vs
  New York City FC New York City FC
   
  Nu Stadium
•  
  @
  Atlanta United FC Atlanta United FC
   
  Mercedes-Benz Stadium
•  
  @
  New York Red Bulls Red Bulls
   
  Red Bull Arena
•  
  vs
  FC Cincinnati FC Cincinnati
   
  Nu Stadium
•  
  @
  New England Revolution Revolution
   
  Gillette Stadium
•  
  vs
  Charlotte FC Charlotte FC
   
  Nu Stadium