•  
  vs
  New York Red Bulls Red Bulls
  0-0
  Geodis Park
•  
  @
  Colorado Rapids Rapids
  1-1
  Dick's Sporting Goods Park
•  
  vs
  Los Angeles Galaxy Galaxy
  2-2
  Geodis Park
•  
  vs
  Charlotte FC Charlotte FC
  2-1
  Geodis Park
•  
  @
  Los Angeles FC Los Angeles FC
  5-0
  BMO Stadium
•  
  vs
  Columbus Crew Crew
  2-2
  GEODIS Park
•  
  vs
  Philadelphia Union Union
  2-1
  Geodis Park
•  
  @
  Inter Miami CF Inter Miami CF
  3-1
  Chase Stadium
•  
  vs
  San Jose Earthquakes Earthquakes
  1-1
  Geodis Park
•  
  vs
  CF Montreal CF Montreal
  4-1
  Geodis Park
•  
  @
  Charlotte FC Charlotte FC
  1-0
  Bank of America Stadium
•  
  vs
  Toronto FC Toronto FC
  2-0
  Geodis Park
•  
  vs
  Atlanta United FC Atlanta United FC
  1-1
  Geodis Park
•  
  @
  CF Montreal CF Montreal
  0-0
  Saputo Stadium
•  
  @
  FC Cincinnati FC Cincinnati
  2-0
  TQL Stadium
•  
  vs
  New England Revolution Revolution
  2-1
  Geodis Park
•  
  @
  New York Red Bulls Red Bulls
  0-0
  Red Bull Arena
•  
  @
  Toronto FC Toronto FC
  2-1
  BMO Field
•  
  vs
  New York City FC New York City FC
  1-0
  Geodis Park
•  
  vs
  Inter Miami CF Inter Miami CF (+0.5)
   
  GEODIS Park
•  
  @
  Columbus Crew Crew (-1)
   
  Lower.com Field
•  
  @
  Portland Timbers Timbers
   
  Providence Park
•  
  @
  D.C. United D.C. United
   
  Audi Field
•  
  vs
  Orlando City SC Orlando City SC
   
  GEODIS Park
•  
  @
  Philadelphia Union Union
   
  Subaru Park
•  
  vs
  Austin FC Austin FC
   
  GEODIS Park
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  @
  Atlanta United FC Atlanta United FC
   
  Mercedes-Benz Stadium
•  
  vs
  Chicago Fire Fire
   
  GEODIS Park
•  
  vs
  FC Cincinnati FC Cincinnati
   
  GEODIS Park
•  
  @
  New England Revolution Revolution
   
  Gillette Stadium
•  
  vs
  D.C. United D.C. United
   
  GEODIS Park
•  
  @
  New York City FC New York City FC
   
  TBC
•  
  @
  Chicago Fire Fire
   
  Soldier Field

Pool Play

•  
  vs
  Mazatlán Mazatlán
   
  GEODIS Park
•  
  @
  New England Revolution Revolution
   
  Gillette Stadium