•  
  vs
  New England Revolution Revolution
  4-1
  Geodis Park
•  
  vs
  Atlético Ottawa Atlético Ottawa
  5-0
  GEODIS Park
•  
  @
  FC Dallas FC Dallas
  0-0
  Toyota Stadium
•  
  vs
  Minnesota United Minnesota United
  3-1
  Geodis Park
•  
  @
  Columbus Crew Crew
  1-0
  ScottsMiracle-Gro Field
•  
  vs
  Orlando City SC Orlando City SC
  5-0
  Geodis Park
•  
  @
  Chicago Fire Fire
  1-0
  Soldier Field
•  
  @
  Charlotte FC Charlotte FC
  2-1
  Bank of America Stadium
•  
  @
  Atlanta United FC Atlanta United FC
  2-0
  Mercedes-Benz Stadium
•  
  vs
  Charlotte FC Charlotte FC
  4-2
  Geodis Park
•  
  @
  Philadelphia Union Union
  0-0
  Subaru Park
•  
  vs
  D.C. United D.C. United (+1)
   
  GEODIS Park
•  
  @
  New England Revolution Revolution (+0.5)
   
  Gillette Stadium
•  
  vs
  Los Angeles FC Los Angeles FC (+0.5)
   
  GEODIS Park
•  
  vs
  New York City FC New York City FC
   
  Geodis Park
•  
  vs
  Leon Leon
   
  GEODIS Park
•  
  vs
  San Luis San Luis
   
  GEODIS Park
•  
  @
  Monterrey Monterrey
   
  GEODIS Park

Knockout (Two Legs)

•  
  vs
  Inter Miami CF Inter Miami CF
  0-0
  GEODIS Park
•  
  @
  Inter Miami CF Inter Miami CF
  1-1
  Chase Stadium
•  
  vs
  America America
  0-0
  GEODIS Park
•  
  @
  America America
  1-0
  Estadio Banorte
•  
  vs
  Tigres Tigres
  1-0
  GEODIS Park
•  
  @
  Tigres Tigres
  1-0
  Estadio Universitario

Regular Season

•  
  vs
  Atlanta United FC Atlanta United FC
   
  GEODIS Park
•  
  vs
  CF Montreal CF Montreal
   
  GEODIS Park
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  @
  D.C. United D.C. United
   
  Audi Field
•  
  vs
  Inter Miami CF Inter Miami CF
   
  GEODIS Park
•  
  @
  New York Red Bulls Red Bulls
   
  Red Bull Arena
•  
  vs
  Columbus Crew Crew
   
  GEODIS Park
•  
  vs
  FC Cincinnati FC Cincinnati
   
  GEODIS Park
•  
  @
  New York City FC New York City FC
   
  Yankee Stadium
•  
  @
  Toronto FC Toronto FC
   
  BMO Field
•  
  @
  Inter Miami CF Inter Miami CF
   
  Nu Stadium
•  
  vs
  Chicago Fire Fire
   
  GEODIS Park
•  
  vs
  Toronto FC Toronto FC
   
  GEODIS Park
•  
  @
  Austin FC Austin FC
   
  Q2 Stadium
•  
  vs
  Sporting Kansas City Sporting Kansas City
   
  GEODIS Park
•  
  @
  San Jose Earthquakes Earthquakes
   
  PayPal Park
•  
  @
  CF Montreal CF Montreal
   
  Stade Saputo
•  
  vs
  Philadelphia Union Union
   
  GEODIS Park
•  
  vs
  New York Red Bulls Red Bulls
   
  GEODIS Park
•  
  @
  FC Cincinnati FC Cincinnati
   
  TQL Stadium