•  
  vs
  CF Montreal CF Montreal
  5-0
  Snapdragon Stadium
•  
  vs
  St. Louis CITY SC St. Louis CITY SC
  2-0
  Snapdragon Stadium
•  
  @
  Sporting Kansas City Sporting Kansas City
  1-0
  Sporting Park
•  
  @
  FC Dallas FC Dallas
  3-3
  Toyota Stadium
•  
  vs
  Real Salt Lake Real Salt Lake
  2-2
  Snapdragon Stadium
•  
  @
  San Jose Earthquakes Earthquakes
  3-0
  PayPal Park
•  
  vs
  Minnesota United Minnesota United
  2-1
  Snapdragon Stadium
•  
  @
  Real Salt Lake Real Salt Lake
  4-2
  America First Field
•  
  @
  Houston Dynamo Dynamo
  1-0
  Shell Energy Stadium
•  
  vs
  Portland Timbers Timbers
  2-1
  Snapdragon Stadium
•  
  vs
  Los Angeles FC Los Angeles FC
  2-2
  Snapdragon Stadium
•  
  @
  Seattle Sounders Sounders
  1-1
  Lumen Field
•  
  vs
  Austin FC Austin FC
  5-0
  Snapdragon Stadium
•  
  vs
  FC Cincinnati FC Cincinnati
  3-3
  Snapdragon Stadium
•  
  vs
  Vancouver Whitecaps Whitecaps
  4-2
  Snapdragon Stadium
•  
  @
  America America
   
  Mexico City Stadium
•  
  vs
  Tijuana Tijuana
   
  Snapdragon Stadium
•  
  vs
  Puebla Puebla
   
  Snapdragon Stadium

Knockout (Two Legs)

•  
  vs
  Toluca Toluca
  3-2
  Snapdragon Stadium
•  
  @
  Toluca Toluca
  4-0
  Estadio Nemesio Díez Riega

Regular Season

•  
  @
  Colorado Rapids Rapids
   
  Dick's Sporting Goods Park
•  
  vs
  FC Dallas FC Dallas
   
  Snapdragon Stadium
•  
  @
  Minnesota United Minnesota United
   
  Allianz Field
•  
  @
  Los Angeles FC Los Angeles FC
   
  BMO Stadium
•  
  @
  Portland Timbers Timbers
   
  Providence Park
•  
  vs
  Colorado Rapids Rapids
   
  Snapdragon Stadium
•  
  vs
  Los Angeles Galaxy Galaxy
   
  Snapdragon Stadium
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  vs
  San Jose Earthquakes Earthquakes
   
  Snapdragon Stadium
•  
  vs
  Philadelphia Union Union
   
  Snapdragon Stadium
•  
  @
  Inter Miami CF Inter Miami CF
   
  Nu Stadium
•  
  @
  Austin FC Austin FC
   
  Q2 Stadium
•  
  @
  New York Red Bulls Red Bulls
   
  Sport Illustrated Stadium
•  
  vs
  Houston Dynamo Dynamo
   
  Snapdragon Stadium
•  
  @
  Los Angeles Galaxy Galaxy
   
  Dignity Health Sports Park
•  
  vs
  Seattle Sounders Sounders
   
  Snapdragon Stadium
•  
  @
  Vancouver Whitecaps Whitecaps
   
  BC Place Vancouver
•  
  @
  St. Louis CITY SC St. Louis CITY SC
   
  Energizer Park
•  
  vs
  Sporting Kansas City Sporting Kansas City
   
  Snapdragon Stadium