•  
  @
  Philadelphia Union Union
  2-2
  Subaru Park
•  
  vs
  FC Cincinnati FC Cincinnati
  2-1
  Soldier Field
•  
  @
  Columbus Crew Crew
  2-1
  Lower.com Field
•  
  vs
  CF Montreal CF Montreal
  4-3
  Soldier Field
•  
  @
  New England Revolution Revolution
  1-1
  Gillette Stadium
•  
  @
  Atlanta United FC Atlanta United FC
  3-0
  Mercedes-Benz Stadium
•  
  vs
  Houston Dynamo Dynamo
  2-1
  Soldier Field
•  
  @
  New York Red Bulls Red Bulls
  0-0
  Red Bull Arena
•  
  vs
  Real Salt Lake Real Salt Lake
  4-0
  Soldier Field
•  
  vs
  Atlanta United FC Atlanta United FC
  0-0
  Soldier Field
•  
  vs
  New England Revolution Revolution
  1-0
  Soldier Field
•  
  @
  St. Louis CITY SC St. Louis CITY SC
  3-1
  Citypark
•  
  vs
  Charlotte FC Charlotte FC
  1-0
  Soldier Field
•  
  vs
  Columbus Crew Crew
  3-1
  Soldier Field
•  
  @
  D.C. United D.C. United (-1)
   
  Audi Field
•  
  vs
  Orlando City SC Orlando City SC (+1)
   
  Soldier Field
•  
  vs
  Los Angeles Galaxy Galaxy
   
  Soldier Field
•  
  @
  Toronto FC Toronto FC
   
  BMO Field
•  
  @
  Orlando City SC Orlando City SC
   
  Exploria Stadium
•  
  @
  Seattle Sounders Sounders
   
  Lumen Field
•  
  vs
  Philadelphia Union Union
   
  Soldier Field
•  
  @
  San Jose Earthquakes Earthquakes
   
  PayPal Park
•  
  vs
  New York City FC New York City FC
   
  Soldier Field
•  
  @
  FC Cincinnati FC Cincinnati
   
  TQL Stadium
•  
  @
  Inter Miami CF Inter Miami CF
   
  Chase Stadium
•  
  @
  New York City FC New York City FC
   
  Citi Field
•  
  vs
  Inter Miami CF Inter Miami CF
   
  Soldier Field
•  
  vs
  D.C. United D.C. United
   
  Soldier Field
•  
  vs
  New York Red Bulls Red Bulls
   
  Soldier Field
•  
  @
  Nashville SC Nashville SC
   
  GEODIS Park
•  
  @
  CF Montreal CF Montreal
   
  Stade Saputo
•  
  vs
  Toronto FC Toronto FC
   
  Soldier Field
•  
  @
  Charlotte FC Charlotte FC
   
  Bank of America Stadium
•  
  vs
  Nashville SC Nashville SC
   
  Soldier Field

Pool Play

•  
  @
  Sporting Kansas City Sporting Kansas City
   
  Children's Mercy Park
•  
  @
  Toluca Toluca
   
  SeatGeek Stadium