•  
  @
  Houston Dynamo Dynamo
  2-1
  Shell Energy Stadium
•  
  vs
  CF Montreal CF Montreal
  3-0
  Soldier Field
•  
  @
  Columbus Crew Crew
  0-0
  ScottsMiracle-Gro Field
•  
  vs
  D.C. United D.C. United
  2-1
  Soldier Field
•  
  @
  Philadelphia Union Union
  2-1
  Subaru Park
•  
  vs
  Nashville SC Nashville SC
  1-0
  Soldier Field
•  
  vs
  Atlanta United FC Atlanta United FC
  1-0
  Soldier Field
•  
  @
  FC Cincinnati FC Cincinnati
  3-3
  TQL Stadium
•  
  vs
  Sporting Kansas City Sporting Kansas City
  5-0
  Soldier Field
•  
  vs
  FC Cincinnati FC Cincinnati
  3-2
  Soldier Field
•  
  vs
  New York Red Bulls Red Bulls (+1)
   
  Soldier Field
•  
  @
  D.C. United D.C. United
   
  Audi Field
•  
  @
  CF Montreal CF Montreal
   
  Saputo Stadium
•  
  vs
  Toronto FC Toronto FC
   
  Soldier Field
•  
  vs
  Necaxa Necaxa
   
  Soldier Field
•  
  vs
  Santos Laguna Santos Laguna
   
  Soldier Field
•  
  @
  Cruz Azul Cruz Azul
   
  Estadio Cuauhtemoc

Regular Season

•  
  vs
  Vancouver Whitecaps Whitecaps
   
  Soldier Field
•  
  @
  Inter Miami CF Inter Miami CF
   
  Chase Stadium
•  
  @
  New York City FC New York City FC
   
  Yankee Stadium
•  
  vs
  Charlotte FC Charlotte FC
   
  Soldier Field
•  
  vs
  Portland Timbers Timbers
   
  Soldier Field
•  
  @
  Orlando City SC Orlando City SC
   
  Inter&Co Stadium
•  
  @
  New York Red Bulls Red Bulls
   
  Sport Illustrated Stadium
•  
  @
  Seattle Sounders Sounders
   
  Lumen Field
•  
  @
  Toronto FC Toronto FC
   
  BMO Field
•  
  vs
  Inter Miami CF Inter Miami CF
   
  Soldier Field
•  
  vs
  New England Revolution Revolution
   
  Soldier Field
•  
  @
  Nashville SC Nashville SC
   
  Geodis Park
•  
  @
  Charlotte FC Charlotte FC
   
  Bank of America Stadium
•  
  vs
  New York City FC New York City FC
   
  Soldier Field
•  
  vs
  Philadelphia Union Union
   
  Soldier Field
•  
  @
  New England Revolution Revolution
   
  Gillette Stadium
•  
  @
  Atlanta United FC Atlanta United FC
   
  Mercedes-Benz Stadium
•  
  vs
  Orlando City SC Orlando City SC
   
  Soldier Field
•  
  @
  Colorado Rapids Rapids
   
  Dick's Sporting Goods Park
•  
  vs
  Columbus Crew Crew
   
  Soldier Field