August 2026

•  
  vs
  Los Angeles Chargers Chargers
   
  NRG Stadium
•  
  vs
  Las Vegas Raiders Raiders
   
  NRG Stadium
•  
  @
  Carolina Panthers Panthers
   
  Bank of America Stadium

September 2026

•  
  vs
  Buffalo Bills Bills (-1.5)
   
  NRG Stadium
•  
  vs
  Cincinnati Bengals Bengals (+2.5)
   
  NRG Stadium
•  
  @
  Indianapolis Colts Colts (+1.5)
   
  Lucas Oil Stadium

October 2026

•  
  vs
  Dallas Cowboys Cowboys (+2.5)
   
  NRG Stadium
•  
  @
  Tennessee Titans Titans (+3.5)
   
  Nissan Stadium
•  
  @
  Jacksonville Jaguars Jaguars (PK)
   
  Wembley Stadium
•  
  vs
  New York Giants Giants (+5.5)
   
  NRG Stadium

November 2026

•  
  @
  Los Angeles Chargers Chargers (-1.5)
   
  SoFi Stadium
•  
  @
  Cleveland Browns Browns (+4.5)
   
  Huntington Bank Field
•  
  vs
  Indianapolis Colts Colts (+5.5)
   
  NRG Stadium
•  
  vs
  Baltimore Ravens Ravens (+1.5)
   
  NRG Stadium

December 2026

•  
  @
  Pittsburgh Steelers Steelers (+1.5)
   
  Acrisure Stadium
•  
  @
  Washington Commanders Commanders (+2.5)
   
  Northwest Stadium
•  
  vs
  Jacksonville Jaguars Jaguars (+3)
   
  NRG Stadium
•  
  @
  Philadelphia Eagles Eagles (-2.5)
   
  Lincoln Financial Field

January 2027

•  
  @
  Green Bay Packers Packers (-2.5)
   
  Lambeau Field
•  
  vs
  Tennessee Titans Titans
   
  NRG Stadium