Preseason

•  
  @
  New York Yankees Yankees
  20-3
  George M. Steinbrenner Field
•  
  vs
  Baltimore Orioles Orioles
  4-4
  Publix Field at Joker Marchant Stadium
•  
  vs
  Minnesota Twins Twins
  3-0
  Publix Field at Joker Marchant Stadium
•  
  @
  Atlanta Braves Braves
  8-1
  CoolToday Park
•  
  vs
  Toronto Blue Jays Blue Jays
  4-4
  Publix Field at Joker Marchant Stadium
•  
  @
  Philadelphia Phillies Phillies
  5-3
  BayCare Ballpark
•  
  @
  Baltimore Orioles Orioles
  6-5
  Ed Smith Stadium
•  
  vs
  Philadelphia Phillies Phillies
  16-8
  Publix Field at Joker Marchant Stadium
•  
  @
  Tampa Bay Rays Rays
  12-3
  Charlotte Sports Park
•  
  vs
  Toronto Blue Jays Blue Jays
  4-4
  Publix Field at Joker Marchant Stadium
•  
  vs
  Atlanta Braves Braves
  5-2
  Publix Field at Joker Marchant Stadium
•  
  vs
  Boston Red Sox Red Sox
  11-3
  Publix Field at Joker Marchant Stadium
•  
  vs
  Pittsburgh Pirates Pirates
  5-3
  Publix Field at Joker Marchant Stadium
•  
  @
  Toronto Blue Jays Blue Jays
  5-0
  TD Ballpark
•  
  vs
  Tampa Bay Rays Rays
  4-4
  Publix Field at Joker Marchant Stadium
•  
  @
  Boston Red Sox Red Sox
  7-2
  JetBlue Park
•  
  @
  Minnesota Twins Twins
  2-1
  Lee Health Sports Complex
•  
  vs
  New York Yankees Yankees
  4-3
  Publix Field at Joker Marchant Stadium
•  
  vs
  Pittsburgh Pirates Pirates
  7-5
  Publix Field at Joker Marchant Stadium
•  
  @
  Toronto Blue Jays Blue Jays
  6-1
  TD Ballpark
•  
  @
  New York Yankees Yankees
  12-1
  George M. Steinbrenner Field
•  
  vs
  Philadelphia Phillies Phillies
  13-6
  Publix Field at Joker Marchant Stadium
•  
  vs
  Baltimore Orioles Orioles
  1-1
  Publix Field at Joker Marchant Stadium
•  
  @
  Pittsburgh Pirates Pirates
  3-1
  LECOM Park
•  
  @
  Philadelphia Phillies Phillies
  4-4
  BayCare Ballpark
•  
  vs
  New York Yankees Yankees
  3-1
  Publix Field at Joker Marchant Stadium
•  
  @
  Colorado Rockies Rockies
  6-5
  Salt River Fields at Talking Stick
•  
  @
  Colorado Rockies Rockies
  11-8
  Salt River Fields at Talking Stick

Regular Season

•  
  @
  San Diego Padres Padres
  8-2
  Petco Park
•  
  @
  San Diego Padres Padres
  5-2
  Petco Park
•  
  @
  San Diego Padres Padres
  3-0
  Petco Park
•  
  @
  Arizona Diamondbacks Diamondbacks
  9-6
  Chase Field
•  
  @
  Arizona Diamondbacks Diamondbacks
  7-5
  Chase Field
•  
  @
  Arizona Diamondbacks Diamondbacks
  1-0
  Chase Field
•  
  vs
  St. Louis Cardinals Cardinals
  4-0
  Comerica Park
•  
  vs
  St. Louis Cardinals Cardinals
  11-6
  Comerica Park
•  
  vs
  St. Louis Cardinals Cardinals
  5-3
  Comerica Park
•  
  @
  Minnesota Twins Twins
  7-3
  Target Field
•  
  @
  Minnesota Twins Twins
  4-2
  Target Field
•  
  @
  Minnesota Twins Twins
  8-6
  Target Field
•  
  @
  Minnesota Twins Twins
  3-1
  Target Field
•  
  vs
  Miami Marlins Marlins
  2-0
  Comerica Park
•  
  vs
  Miami Marlins Marlins
  6-1
  Comerica Park
•  
  vs
  Miami Marlins Marlins
  8-2
  Comerica Park
•  
  vs
  Kansas City Royals Royals
  2-1
  Comerica Park
•  
  vs
  Kansas City Royals Royals
  2-1
  Comerica Park
•  
  vs
  Kansas City Royals Royals
  10-9
  Comerica Park
•  
  @
  Boston Red Sox Red Sox
  1-0
  Fenway Park
•  
  @
  Boston Red Sox Red Sox
  4-1
  Fenway Park
•  
  @
  Boston Red Sox Red Sox
  6-2
  Fenway Park
•  
  @
  Boston Red Sox Red Sox
  8-6
  Fenway Park
•  
  vs
  Milwaukee Brewers Brewers
  12-4
  Comerica Park
•  
  vs
  Milwaukee Brewers Brewers
  5-2
  Comerica Park
•  
  vs
  Milwaukee Brewers Brewers
  5-4
  Comerica Park
•  
  @
  Cincinnati Reds Reds
  9-8
  Great American Ball Park
•  
  @
  Cincinnati Reds Reds
  9-2
  Great American Ball Park
•  
  @
  Cincinnati Reds Reds
  8-3
  Great American Ball Park
•  
  @
  Atlanta Braves Braves
  5-2
  Truist Park
•  
  @
  Atlanta Braves Braves
  4-3
  Truist Park
•  
  @
  Atlanta Braves Braves
  5-2
  Truist Park
•  
  vs
  Texas Rangers Rangers
  5-4
  Comerica Park
•  
  vs
  Texas Rangers Rangers
  5-1
  Comerica Park
•  
  vs
  Texas Rangers Rangers
  7-1
  Comerica Park
•  
  vs
  Boston Red Sox Red Sox
  5-4
  Comerica Park
•  
  vs
  Boston Red Sox Red Sox
  10-3
  Comerica Park
•  
  vs
  Boston Red Sox Red Sox
  4-0
  Comerica Park
•  
  @
  Kansas City Royals Royals
  4-3
  Kauffman Stadium
•  
  @
  Kansas City Royals Royals
  5-1
  Kauffman Stadium
•  
  @
  Kansas City Royals Royals
  6-3
  Kauffman Stadium
•  
  @
  New York Mets Mets
  10-2
  Citi Field
•  
  @
  New York Mets Mets
  3-2
  Citi Field
•  
  @
  New York Mets Mets
  9-4
  Citi Field
•  
  vs
  Toronto Blue Jays Blue Jays
  3-2
  Comerica Park
•  
  vs
  Toronto Blue Jays Blue Jays
  2-1
  Comerica Park
•  
  vs
  Toronto Blue Jays Blue Jays
  4-1
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
  8-2
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
  4-3
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
  3-2
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
  3-1
  Comerica Park
•  
  @
  Baltimore Orioles Orioles
  7-4
  Oriole Park at Camden Yards
•  
  @
  Baltimore Orioles Orioles
  5-3
  Oriole Park at Camden Yards
•  
  @
  Baltimore Orioles Orioles
  4-1
  Oriole Park at Camden Yards
•  
  vs
  Los Angeles Angels Angels
  10-6
  Comerica Park
•  
  vs
  Los Angeles Angels Angels
  4-0
  Comerica Park
•  
  vs
  Los Angeles Angels Angels
  7-1
  Comerica Park
•  
  @
  Chicago White Sox White Sox
  4-3
  Rate Field
•  
  @
  Chicago White Sox White Sox
  7-1
  Rate Field
•  
  @
  Chicago White Sox White Sox
  2-1
  Rate Field
•  
  @
  Tampa Bay Rays Rays
  10-9
  Tropicana Field
•  
  @
  Tampa Bay Rays Rays
  8-0
  Tropicana Field
•  
  @
  Tampa Bay Rays Rays
  7-2
  Tropicana Field
•  
  vs
  Seattle Mariners Mariners
  7-3
  Comerica Park
•  
  vs
  Seattle Mariners Mariners
  4-0
  Comerica Park
•  
  vs
  Seattle Mariners Mariners
  5-4
  Comerica Park
•  
  vs
  Minnesota Twins Twins
  10-4
  Comerica Park
•  
  vs
  Minnesota Twins Twins
  6-4
  Comerica Park
•  
  vs
  Minnesota Twins Twins
  11-0
  Comerica Park
•  
  @
  Cleveland Guardians Guardians
  3-2
  Progressive Field
•  
  @
  Cleveland Guardians Guardians
  3-1
  Progressive Field
•  
  @
  Houston Astros Astros
  9-3
  Daikin Park
•  
  @
  Houston Astros Astros
  4-2
  Daikin Park
•  
  @
  Houston Astros Astros
  4-2
  Daikin Park
•  
  vs
  Chicago White Sox White Sox
  4-3
  Comerica Park
•  
  vs
  Chicago White Sox White Sox
  4-1
  Comerica Park
•  
  vs
  Chicago White Sox White Sox
  5-4
  Comerica Park
•  
  vs
  New York Yankees Yankees
  5-3
  Comerica Park
•  
  vs
  New York Yankees Yankees
  4-3
  Comerica Park
•  
  vs
  New York Yankees Yankees
  4-2
  Comerica Park
•  
  vs
  Houston Astros Astros
  2-1
  Comerica Park
•  
  vs
  Houston Astros Astros
  8-0
  Comerica Park
•  
  vs
  Houston Astros Astros
  8-6
  Comerica Park
•  
  vs
  Houston Astros Astros
  7-5
  Comerica Park
•  
  @
  New York Yankees Yankees
  7-3
  Yankee Stadium
•  
  @
  New York Yankees Yankees
  9-3
  Yankee Stadium
•  
  @
  New York Yankees Yankees
  6-2
  Yankee Stadium
•  
  @
  Texas Rangers Rangers (-1.5)
   
  Globe Life Field
•  
  @
  Texas Rangers Rangers
   
  Globe Life Field
•  
  @
  Texas Rangers Rangers
   
  Globe Life Field
•  
  vs
  Sacramento Athletics Athletics
   
  Comerica Park
•  
  vs
  Sacramento Athletics Athletics
   
  Comerica Park
•  
  vs
  Sacramento Athletics Athletics
   
  Comerica Park
•  
  vs
  Philadelphia Phillies Phillies
   
  Comerica Park
•  
  vs
  Philadelphia Phillies Phillies
   
  Comerica Park
•  
  vs
  Philadelphia Phillies Phillies
   
  Comerica Park
•  
  @
  Los Angeles Angels Angels
   
  Angel Stadium
•  
  @
  Los Angeles Angels Angels
   
  Angel Stadium
•  
  @
  Los Angeles Angels Angels
   
  Angel Stadium
•  
  @
  Chicago Cubs Cubs
   
  Wrigley Field
•  
  @
  Chicago Cubs Cubs
   
  Wrigley Field
•  
  @
  Chicago Cubs Cubs
   
  Wrigley Field
•  
  vs
  Kansas City Royals Royals
   
  Comerica Park
•  
  vs
  Kansas City Royals Royals
   
  Comerica Park
•  
  vs
  Kansas City Royals Royals
   
  Comerica Park
•  
  vs
  Kansas City Royals Royals
   
  Comerica Park
•  
  vs
  Baltimore Orioles Orioles
   
  Comerica Park
•  
  vs
  Baltimore Orioles Orioles
   
  Comerica Park
•  
  vs
  Baltimore Orioles Orioles
   
  Comerica Park
•  
  @
  Sacramento Athletics Athletics
   
  Sutter Health Park
•  
  @
  Sacramento Athletics Athletics
   
  Sutter Health Park
•  
  @
  Sacramento Athletics Athletics
   
  Sutter Health Park
•  
  @
  Seattle Mariners Mariners
   
  T-Mobile Park
•  
  @
  Seattle Mariners Mariners
   
  T-Mobile Park
•  
  @
  Seattle Mariners Mariners
   
  T-Mobile Park
•  
  @
  San Francisco Giants Giants
   
  Oracle Park
•  
  @
  San Francisco Giants Giants
   
  Oracle Park
•  
  @
  San Francisco Giants Giants
   
  Oracle Park
•  
  vs
  Cleveland Guardians Guardians
   
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
   
  Comerica Park
•  
  vs
  Cleveland Guardians Guardians
   
  Comerica Park
•  
  vs
  Chicago White Sox White Sox
   
  Comerica Park
•  
  vs
  Chicago White Sox White Sox
   
  Comerica Park
•  
  vs
  Chicago White Sox White Sox
   
  Comerica Park
•  
  @
  Pittsburgh Pirates Pirates
   
  PNC Park
•  
  @
  Pittsburgh Pirates Pirates
   
  PNC Park
•  
  @
  Pittsburgh Pirates Pirates
   
  PNC Park
•  
  @
  Kansas City Royals Royals
   
  Kauffman Stadium
•  
  @
  Kansas City Royals Royals
   
  Kauffman Stadium
•  
  @
  Kansas City Royals Royals
   
  Kauffman Stadium
•  
  vs
  Tampa Bay Rays Rays
   
  Comerica Park
•  
  vs
  Tampa Bay Rays Rays
   
  Comerica Park
•  
  vs
  Tampa Bay Rays Rays
   
  Comerica Park
•  
  vs
  Los Angeles Dodgers Dodgers
   
  Comerica Park
•  
  vs
  Los Angeles Dodgers Dodgers
   
  Comerica Park
•  
  vs
  Los Angeles Dodgers Dodgers
   
  Comerica Park
•  
  @
  Minnesota Twins Twins
   
  Target Field
•  
  @
  Minnesota Twins Twins
   
  Target Field
•  
  @
  Minnesota Twins Twins
   
  Target Field
•  
  @
  Cleveland Guardians Guardians
   
  Progressive Field
•  
  @
  Cleveland Guardians Guardians
   
  Progressive Field
•  
  @
  Cleveland Guardians Guardians
   
  Progressive Field
•  
  @
  Cleveland Guardians Guardians
   
  Progressive Field
•  
  vs
  Minnesota Twins Twins
   
  Comerica Park
•  
  vs
  Minnesota Twins Twins
   
  Comerica Park
•  
  vs
  Minnesota Twins Twins
   
  Comerica Park
•  
  vs
  Colorado Rockies Rockies
   
  Comerica Park
•  
  vs
  Colorado Rockies Rockies
   
  Comerica Park
•  
  vs
  Colorado Rockies Rockies
   
  Comerica Park
•  
  @
  Toronto Blue Jays Blue Jays
   
  Rogers Centre
•  
  @
  Toronto Blue Jays Blue Jays
   
  Rogers Centre
•  
  @
  Toronto Blue Jays Blue Jays
   
  Rogers Centre
•  
  @
  Chicago White Sox White Sox
   
  Rate Field
•  
  @
  Chicago White Sox White Sox
   
  Rate Field
•  
  @
  Chicago White Sox White Sox
   
  Rate Field
•  
  @
  Chicago White Sox White Sox
   
  Rate Field
•  
  vs
  Washington Nationals Nationals
   
  Comerica Park
•  
  vs
  Washington Nationals Nationals
   
  Comerica Park
•  
  vs
  Washington Nationals Nationals
   
  Comerica Park
•  
  vs
  Pittsburgh Pirates Pirates
   
  Comerica Park
•  
  vs
  Pittsburgh Pirates Pirates
   
  Comerica Park
•  
  vs
  Pittsburgh Pirates Pirates
   
  Comerica Park

•  
  @
  Cleveland Guardians Guardians
   
  Progressive Field