| Sep 27 | | 50 | Reds 2, Astros 3Final | Rodriguez, Astros end Reds' winning streak at 6 |
| Sep 28 | | 55 | Astros 8, Phillies 2Final | Phillies' lead trimmed to 4 with another loss |
| Sep 29 | | 15 | Astros 4, Phillies 7Final | Feliz, Happ help Phillies reduce magic number to 1 |
| Sep 30 | | 15 | Astros 3, Phillies 10Final | Phillies clinch 3rd straight NL East title |
| Oct 1 | | 46 | Astros 5, Phillies 3Final | Cliff Lee shaky in playoff tuneup as Phillies lose |
| Oct 2 | | 15 | Astros 1, Mets 7Final | Maine helps Mets beat Astros 7-1 |
| Oct 3 | | 10 | Astros 1, Mets 5Final | Misch leads Mets past Astros |
| Oct 4 | | 10 | Astros 0, Mets 4Final | Figueroa pitches shutout, Mets beat Astros 4-0 |
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